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In addition, a series of new agents are in clinical development, including the AR antagonists ARN-509 44 and EPI-001 that directly target the AR, as well as orteronel (TAK-700) 45,46 and galeterone (TOK-001) 47 that indirectly target the AR

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Key Features GLP-1 receptor agonist Activates incretin GPCR signaling Relevant to insulin secretion and glucose homeostasis Useful for diabetes and obesity model research Applications GLP-1R functional assays cAMP and incretin signaling studies -cell insulin secretion research Metabolic disease and obesity pharmacology models More Information GLP-1R agonist DMB GLP-1 receptor agonist DMB GLP-1RagonistDMB GLP-1 GLP-1 receptor Agonist cAMP signaling GPCR signaling GLP-1R functional assays cAMP and incretin signaling studies -cell insulin secretion research Metabolic disease and obesity pharmacology models metabolism diabetes research obesity research GPCR pharmacology signal transduction GPCR CAS 281209-71-0 Axon Medchem Axon 1907 Supplier Vendor References LB Knudsen et al