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In summary, protein-based transporters have strong potential to translate natural GM modulators into clinically relevant nutraceuticals and therapeutics
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Although viral vectors are considered relatively safe, there are still some precautions and concerns around them, especially after 1999 when a 20-year-old man died due to an allergic reaction to the vehicle (inactive carrier) during a gene therapy clinical study in Pennsylvania [5]
doi: 10.1007/s00223-017-0376-y 92 ColaianniGCuscitoCMongelliTPignataroPBuccolieroCLiuPet al
body mass index (BMI) of 21.033.0 kg/m 2 , sedentary lifestyle (defined by Stanford questionnaire, Additional file 1: Table S1), maintain current dietary habits and activity levels, if taking supplements agree to maintain dosing regimen for at least one month prior to baseline and during the study, agree not to start any new supplements, give voluntary, written informed consent to participate
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