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Moreover, it is required for the transport and metabolism of fats and cholesterol within the body, which is important for the healthy support of the endocrine, cardiovascular, and hepatic systems

For example, one study showed that although people treated for 68 weeks with semaglutide (2.4 mg/week) lost an average of 18% of their initial body weight, the majority of this weight was regained within a year following discontinuation of treatment (Figure 7)

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This has resulted in several investigators concluding that its effects are irreversible, since in tissue environments its effects can last many days to weeks (German et al 2015)

If your system doesnt make enough insulin, glucose will stay in your bloodstream, causing blood sugar spikes