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HRP-conjugated secondary antibodies for western blotting were purchased from Cell Signaling Technology

In terms of treatment choices, if C-peptide levels are maintained, the advised algorithm is similar to the ADA/EASD Consensus Report on managing type 2 diabetes (Buse et al, 2020), except it avoids the use of sulfonylureas altogether, as a more rapid deterioration in beta-cell function due to direct stimulation by this drug class cannot be excluded

CagriSema is a fixed-dose combination obesity medication made by Novo Nordisk, the same Danish company that makes Wegovy and Ozempic

"Fibroblast growth factor 21 increases insulin sensitivity through specific expansion of subcutaneous fat." Nature Communications 9.1(2018):272

While both drugs are effective, adding a third hormone (Glucagon) in Retatrutide brings a different side effect profile that researchers are still studying