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Tirzepatide's dual-receptor approach produces sustained weight loss in clinical trials, with patients in the SURMOUNT trials losing 20-22% of baseline body weight over 68 weeks

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Even though there are lots of case reports on melanosis coli which has been reported from north India, there is no case report from this part of the country

Patients were excluded if they had a major cardiovascular event within the last 60 days, type 1 diabetes mellitus, history of pancreatitis, or a history of severe hypoglycemia

Neurodegenerative diseases is metabolic deficiency the root cause