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This evidence suggests that UA can exert neuroprotective effects by regulating microglia

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This activation is responsible for regulating lipid homeostasis by promoting the increased expression of the membrane transporter channels Abca1 and Abcg1, which control cholesterol efflux and thereby prevent lipid toxicity and cellular dysfunction [65]

The two are related but not identical

YangKLiuXLiuYWangXCaoLZhangXet alDC-SIGN and toll-like receptor 4 mediate oxidized low-density lipoprotein-induced inflammatory responses in macrophages