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By imitating hypoxia through HIF prolyl hydroxylase domain enzyme (HIF-PHD) inhibition, HIF stabilizer increases endogenous erythropoietin (EPO)

By Daisy Lin Medical Writer Reviewed April 27, 2026 Bacteriostatic water is sterile water with 0.9% benzyl alcohol added as a preservative

Epacadostat plus pembrolizumab in patients with advanced solid tumors: phase I results from a multicenter, open-label phase I/II trial (ECHO-202/KEYNOTE-037)