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Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, et al

Moreover, the multidrug and toxin extrusion proteins (MATEs) are crucial in the transportation of metformin (Jensen et al., 2016)

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It improves gut microbiota composition and barrier function, thereby reducing systemic inflammation, while simultaneously rebalancing lipid metabolism genes