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Significance was determined by one-way repeated measures analysis of variance, and the HolmSidak method for multiple comparisons versus the control group, using SigmaPlot 10.0 software (Systat Software, San Jose, CA, USA)

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Only small, highly lipophilic molecules can passively diffuse across the barrier (Maiuolo et al., 2018)

By contrast, luminal-type breast cancer cells, which are commonly found in patients with breast cancer with hormone receptor-positive status, are cystine-independent and therefore less affected by cystine deprivation (27,28)