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59 Shafei reported that BCAT1 inhibited the Ras/ERK pathway and activates PI3K/AKT pathway through insulin/IGF-1, ultimately promoting the expression levels of FOXO3a and Nrf2 and regulating the proliferation, migration, and invasion in triple-negative breast cancer (TNBC)

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At trial end, the reduction in glycated hemoglobin (HbA1c) and fasting plasma glucose with TOUJEO titrated to goal was similar to that with LANTUS titrated to goal

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