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This neuroprotection was dose-dependent and mechanistically distinct from IGF-1R-mediated neuroprotection providing the foundational evidence for PEG-MGFs use in CNS neuroprotection research

by contrast, antagonizing NMDA receptors in the hypothalamus has been linked to a reduction in food intake and a decrease in body weight 8

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Filtering of quantifiable proteins and missing values imputation were done as in the discovery untargeted analysis

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