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Whatever their ressemblance to the in vivo BBB, in vitro BBB models must be carefully assessed for their ability to predict accurately the passage of drugs into the CNS in vivo

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Pyrimidine-based small molecules ( 16 ) were identified as GLP-1R agonists by cell-based screening and insulin secretion assays with rodent and human islets (Figure 3)

oleifera leaves are a source of magnesium, which can positively influence milk yield and composition, for example, Magnesium supplementation in cattle diets has been reported to increase milk fat concentration and yield, with one study noting a 12% increase within 4 days (68)

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