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Under these circumstances, BAP31 is cleaved with consequent formation of the p20 fragment, which activates the mitochondrial apoptotic events such as cytochrome c release, resulting in activation of the intrinsic apoptotic pathway [123, 125]

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CRP is synthesized in smooth muscle cells of atherosclerotic lesions with active disease, foam cells, macrophages, lymphocytes, monocytes, and endothelial cells within the atherosclerotic plaque (166170)

doi:10.1124/jpet.111.188946