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In support of this mechanism, GLP-1 application increased surface levels of DAT as measured by LS slice biotinylation 43 (Figures 2a and b)

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The main pathway runs through the hypothalamic-pituitary-adrenal (HPA) axis and its interaction with the hypothalamic-pituitary-gonadal (HPG) axis

Furthermore, there seemed to be a considerable improvement in brain edema

These treatments often require subcutaneous injections or extremely rigid oral dosing schedules, including strict fasting windows and specific water intake, which can lead to low patient adherence and inconsistent clinical data in long-term studies