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Experimental observations in these models include changes in circulating metabolic markers, altered hepatic lipid accumulation, and modulation of gene expression related to energy metabolism pathways

Crosstalk of pyroptosis and cytokine in the tumor microenvironment: from mechanisms to clinical implication

doi: 10.4158/EP.14.8.979 21 MarsoSPDanielsGHBrown-FrandsenKKristensenPMannJFNauckMAet al

Additionally, while announcing its results, Lilly also revealed positive outcomes from the first Phase III weight loss study of the small molecule GLP-1 drug orforglipron

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