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5 Conclusions In summary, the GLP-1R/GCGR dual agonist TB001 effectively mitigates kidney allograft fibrosis and improves graft function, likely through mechanisms involving enhanced lipid metabolism and inhibition of the PKC-, PKC-, and TGF-1/SMAD2/3/Twist pathways

Resmetirom also slightly increased lean mass relative to body weight (Fig

Diabetic foot refers to ulcers that form on the dorsal or plantar part of the foot

Polyethylene glycol is particularly well-tolerated and does not typically cause electrolyte disturbances when used as directed

Demographics such as age, duration of diabetes, medical history and medications were obtained