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Rabbits were divided into four groups and treated for about 3 weeks, control group was named G1 and administered distilled water, while group 2 received CP at a dose of 50 mg per kg per week

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Furthermore, they demonstrated that chondrocyte lipid peroxidation contributed to the oxidation and degradation of collagen, which in turn may aggravate OA by increasing the sensibility of cartilage to mechanical fatigue [51]