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TGH-2 was found to be expressed predominantly in liver but was also present in adipose tissue and kidney and was induced by fasting and inhibited by refeeding

That's significant, but it's not going to make a 60-year-old look 30

It is also used to manage vitamin B12 deficiencies resulting from specific surgeries, diseases of the stomach or gut, and any other genetic disorders affecting vitamin B12 metabolism

Bolton WD, Hofstetter WL, Francis A, Correa AM, Ajani, JA, Bhutani B, Erasmus JJ, Komaki R, Maru D, Mehran RJ, Rice DC, Roth JA, Swisher SG , Vaporciyan AA, Walsh GL, Weaver J, Rhines L

The metabolism of homocysteine: pathways and regulation