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Handb Exp Pharmacol 196:369405 Holme JA, Hongslo JK, Bjrge C, Nelson SD (1991) Comparative cytotoxic effects of acetaminophen ( N -acetyl- p -aminophenol), a non-hepatotoxic regioisomer acetyl- m -aminophenol and their postulated reactive hydroquinone and quinone metabolites in monolayer cultures of mouse hepatocytes

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Graphical Abstract Keywords Familial hypobetalipoproteinemia, Apolipoprotein B, Lipid metabolism disorder, Hepatic steatosis, Liver fibrosis, Monogenic liver disease Introduction Familial hypobetalipoproteinemia (FHBL) type 1 (OMIM 615558) is a rare, autosomal codominant monogenic disorder caused by variants in the apolipoprotein B ( APOB ) gene on chromosome locus 2p24.1