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[1] From this theory, we can propose that stimulating IGF-1 in skin tissue may be a potential effective treatment for regulating skin cell differentiation, improving insulin sensitivity in the skin, reducing keratinocyte proliferation, inhibiting inflammation via stimulation of IL-10 production and up-regulating sebocyte proliferation (via IGF-1 stimulation of 5-Reductase)

The expression of BOLA3 is reduced due to HIF-2-dependent transcriptional inhibition, and its deletion disrupts the integrity of iron-sulfur (Fe-S) clusters, affects the function of two-oxoacid dehydrogenases containing lipoic acid, and regulates glycolysis and mitochondrial respiration

Gene expression profiling, data analysis and pathway analysis Total RNAs from NTAPP-treated cells or non-treated cells were purified and isolated using an RNeasy plus mini kit (Qiagen, Hilden, Germany)

Sure, okay

2008 Dec;159(6):841