[1] [3] As a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, tirzepatide works by enhancing insulin secretion in response to meals, suppressing glucagon release, slowing gastric emptying, and reducing appetite
MT-I is more MC1R-focused in many discussions, but both can cause side effects
Mild to moderate side effects are often observed in the early weeks (~first 6) of medication use and during dose escalation
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Tschuck J, Nair VP, Galhoz A, Ciceri G, Rothenaigner I, Tchieu J, Tai H-M, Stockwell BR et al (2023) Suppression of ferroptosis by vitamin A or antioxidants is essential for neuronal development