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This is important because it suggests the anti-psoriatic activity can be localized to a specific portion of the larger protein, potentially allowing the development of small, targeted peptide therapeutics

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These experiments confirmed that cagrilintide is a potent dual agonist, activating both receptor types, which is crucial for its therapeutic effect on reducing food intake and body weight, as demonstrated in preclinical rat models

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With ~50% of cells in the SVF expressing +CD146+, perivascular cells (pericytes) play a physiological role in vascular development and homeostasis (52)