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Despite that, for a long time, it was believed that no neurons are made in adult brains, the evidence that neurogenesis is also possible in human adult in the SVZ, in the sub-granular zone (SGZ) on the hippocampal dentate gyrus (DG), and in the olfactory bulb (Zhao and Moore, 2018) strikingly reversed that dogma, opening the possibility to employ stem cells as new tools for therapeutic purposes in neural regeneration/repair in diseases and after injuries (Figure 6)

Am J Hum Genet 2001;68:132732

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Individuals with genetic predispositions to Alzheimer disease, those with a history of repeated mild TBI, or people experiencing early subjective cognitive decline might benefit from peptide protocols aimed at maintaining neuronal health before significant degeneration occurs