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Diabetes 54(7):22122218 Meier JJ, Rosenstock J, Hincelin-Mery A, Roy-Duval C, Delfolie A, Coester HV et al (2015) Contrasting effects of lixisenatide and liraglutide on postprandial glycemic control, gastric emptying, and safety parameters in patients with type 2 diabetes on Optimized insulin glargine with or without metformin: a randomized, open-label trial

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The disadvantage is the metabolic disruption of stopping and starting, which may reduce the efficiency of subsequent treatment courses