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Leydig cell aging (Zhang et al., 2020, Aging) FOXO4-DRI improved testosterone secretion and the testicular microenvironment in aged mice by clearing senescent Leydig cells

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This issue of inadequate energy delivery, coupled with the lack of standardisation in treatment parameters (such as wavelength, power, and energy density), and variations in individual anatomical structures and tissue optical properties, collectively contributes to inconsistent clinical research outcomes, limiting the maximisation of PBMT efficacy (8)