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The incorporation of EPA supplementation has shown to have stronger anti-inflammatory and antioxidant effects in treating depression and neurodegenerative diseases in previous studies 99,100 and might be a possible cause for the downregulation of MSG-induced -synuclein overexpression observed in the N-3 PAFAs-treated rats in our study

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(continued) Autoimmune disease Classification Genetically predisposed strains b Autoimmunization c Biological/chemical induction Systemic sclerosis Tight skin (TSK) mouse, (Scleroderma) a Adapted from Cohen & Miller (1994)

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