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This article covers the exact reconstitution protocol used in controlled laboratory settings, the sterile technique required to prevent contamination, and the concentration calculations that ensure dosing precision across multi-week studies

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The method was qualified for the quantification range of 11000 ng/mL with accuracy and precision of 20%, except for at the lower limit of quantification when the accuracy and precision were 25%

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Two independent authors completed the risk of bias assessment (SO and JM)