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Topical application in women with photodamaged skin showed a significant reduction in lines and wrinkles as well as improved skin thickness compared to the placebo and Vitamin K cream after 12 weeks of application

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The proto-oncogenic transcriptional co-activator YAP is also an important factor, which can inhibit ferroptosis upregulation of multiple ferroptosis modulators, including acyl-CoA synthetase long chain family member 4 (ACSL4) and transferrin receptor [15]