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It was beneficial for PD when using ferroptosis inhibitor-iron chelator deferiprone for PD treatment in a randomized controlled trial (Moreau et al., 2018)

This is the most common research configuration

Furthermore, NOS3 knockout mice display increased infarct sizes compared to wild type mice post middle cerebral artery occlusion (MCAO) (Huang et al., 1996)

The prevalence of keratinocytes IR receptors and associated genetic receptor mutations may also partially cause this imbalance to occur

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