In recent years, small molecule antagonists, antisense oligonucleotides, and monoclonal antibodies targeting GCGR have been developed and demonstrated efficacy in improving glycemic control in both rodent models of diabetes and human patients with diabetes 8,9,10,11,12,13
Therapeutic Use Exemptions No Therapeutic Use Exemption pathway exists for BPC-157 because it is not an approved pharmaceutical in any WADA-signatory jurisdiction
Studies of serum metabolites allows for larger cohort sizes and ease of implementation but is an indirect marker of cerebral metabolism that is impacted by GI function/microbial metabolism
Vial planning for a full titration Understanding how many vials you need for a complete titration prevents running out mid-protocol
Avoid shaking, as this can break down the peptide