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On the other hand, GLP-1 retains its enhancing effects on insulin secretion in patients with type 2 diabetes, independent of its plasma levels

Semaglutide, the active ingredient in Ozempic and Wegovy, is a GLP-1 receptor agonist that slows stomach emptying and reduces appetite signals

This line of research helps investigators study how receptor co-activation influences substrate utilization, lipid oxidation pathways, and the balance between stored fat use and lean tissue preservation

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