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High expression of HNF4 in EC may supplement intracellular GSH through a non-xCT-dependent pathway by activating metabolic enzymes involved in methionine metabolism, which may represent a key mechanism underlying ferroptosis resistance in EC
10.2174/187152510791698398 137 SchuettpelzL
International Union of Basic and Clinical Pharmacology
Additionally, the thiol side chain of cysteines serve as potent nucleophiles and react with oxidants and electrophilic species that would otherwise cause damage to the cell
Aqua(Water), Centella Asiatica Leaf Water, Glycerin, Cetyl Ethylhexanoate, Cetearyl Alcohol, Glyceryl Stearate, PEG-100 Stearate, Sorbitan Stearate, Cyclopentasiloxane, 1,2-Hexanediol, Saccharide Hydrolysate, Dimethicone, Cyclohexasiloxane, Stearic Acid, Chlorphenesin, Carbomer, Glyceryl Stearate SE, Caprylyl Glycol, Niacinamide, Glutathione, Xanthan Gum, Potassium Hydroxide, Disodium EDTA, Butylene Glycol, Dipropylene Glycol, Squalane, Asiaticoside, Madecassic Acid, Asiatic Acid, Sodium Hyaluronate, Melaleuca Alternifolia (Tea Tree) Leaf Extract, Hippophae Rhamnoides Fruit Extract, Hydrolyzed Collagen, Beta-Glucan, Nelumbium Speciosum Flower Extract, Artemisia Annua Extract, Oryza Sativa (Rice) Extract, Saccharomyces Ferment, Solanum Melongena (Eggplant) Fruit Extract Ingredients are subject to change at the manufacturer's discretion
