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Tirzepatide, a dual GLP-1 and GIP receptor agonist, has a longer half-life of roughly 5 days in steady-state dosing, though elimination accelerates slightly at higher doses

More data are needed to clarify the effects of GLP-1RAs on the incidence of OA, RA, PsA and axSpA, as well as on disease activity and progression in these conditions

Oral formulations of both compounds typically clear faster than injectable versions because they bypass the subcutaneous depot effect that extends release

Novo Nordisk has vaulted from insulin pioneer to global leader, driven by Ozempic and Wegovy and a market cap above $600B by 2025

Do I need a prescription for GLP-1 medications in Canada