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It is important to note that NTD do not arise from a nutritional deficiency of folate but from metabolic defects that can be corrected by significantly large doses of folic acid at developmentally critical times

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The burden of both T2D and obesity has increased at a rapid pace among metabolic disorders [16], highlighting the urgent need to address these two common and closely linked metabolic disorders as a public health priority

Examples of benzodiazepines that might be, under very careful consideration, used for symptoms such as anxiety and insomnia, include diazepam, lorazepam, and clonazepam