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Individual tolerability and response vary based on baseline glutathione status, nutritional cofactors (B6, B12, folate), and genetic variations in the enzymes that synthesize or recycle glutathione

This makes it important to be cautious if you decide to use a supplement or increase your consumption of glutathione-rich foods

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On the other hand, it is essential to focus on clinical trial endpoints related to disease progression and improvement in antioxidant studies, as these are more meaningful than simply measuring variations in overall survival OS biomarkers or patient mortality

[DOI] [PubMed] [Google Scholar] 43.Winterbourn C.C., Metodiewa D