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We've found that patients who respond best to lipotropic therapy share a common metabolic profile: elevated liver enzymes (ALT, AST) without viral hepatitis, fasting insulin above 10 IU/mL, and weight loss plateaus despite maintaining caloric deficits

Studies have shown that long-term use of GLP-1 medications is generally safe and effective for both diabetes management and weight loss

Case reports CASE 1 On august 2005, a 7-year-old Caucasian Brazilian boy presented to the Oral Diagnosis Clinic (Orocentro), School of Dentistry, State University of Campinas, Piracicaba, So Paulo, Brazil, for evaluation and management of a pigmented macule discovered during routine dental treatment on the attached gingiva of the partial erupted mandibular left permanent canine