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Therefore, experiments conducted on zebrafish embryos prior to this stage do not fall within the scope of the Directive and are exempt from ethical review

These results indicate modest efficacy, with realistic expectations being 0.25-0.5 kg (0.5-1 pound) per week under optimal conditions

Our experience shows that preparation is 90% of the battle

Beyond this time point, the study became an open-label trial whereby all participants received 280mg brodalumab each week

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