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10.1186/1471-2202-9-s2-s15 43 GarreauI.ChanselD.VandermeerschS.FruitierI.PiotJ

Researchers who optimize these surrounding factors consistently report better results than those who rely on the peptide alone

The mechanism was proposed to involve copper-dependent enzymes (notably lysyl oxidase, which catalyzes the cross-linking of collagen and elastin and requires copper as a cofactor), GHK-specific effects on growth factor activity, and downstream gene-expression effects in fibroblasts and other tissue-repair-relevant cell types

The peptide migrates to damaged tissues from injection sites, enabling both local and systemic healing from single injection locations

Always use with caution