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GLP-1 medications like semaglutide (Wegovy) and liraglutide (Saxenda) are MHRA-licensed prescription-only medicines that work by enhancing satiety and slowing gastric emptying rather than boosting metabolism

Who Should Consider GLP-1 Therapy FDA indications for weight loss require: BMI 30 (obesity), or BMI 27 (overweight) with at least one weight-related condition hypertension, type 2 diabetes, dyslipidemia, obstructive sleep apnea, cardiovascular disease, or similar These thresholds set eligibility, but they don't answer the more important question: who benefits most

For those with diabetes, monitoring should include blood glucose checks as clinically indicated and hemoglobin A1c reassessment approximately 3 months after therapy changes, per American Diabetes Association guidelines

Eat protein beforehand: Never drink on an empty stomach