Thats especially true given the mystery for why people with Type 2 diabetes (for which these drugs were used for many years) did not exhibit much in the way of weight loss
The National Weight Control Registry, which tracks individuals who have successfully maintained significant weight loss, identifies common characteristics including high levels of physical activity, regular breakfast consumption, consistent eating patterns across weekdays and weekends, and frequent self-weighing
10.1016/j.neuint.2019.104616 41 MartyV
coli levels in mice After a single subcutaneous injection of liraglutide, a GLP-1RA, followed by a 16-h overnight fast, the relative expression levels of the gut bacterium in the cecal contents of mice were assessed using quantitative PCR
"What we are seeing is a signal that it may slow some of the biological processes associated with aging