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Its extraordinary picomolar potency in spinogenesis assays and its demonstrated efficacy in aged and amnestic animal models position it as one of the most compelling compounds in modern neuroscience research

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Suboptimal medication use comprises (1) underprescribing, (2) polypharmacy or overuse, and (3) high-risk prescribing, such as potentially inappropriate medications (PIMs), prescribing cascades, and anticholinergic and sedative effects