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Aplastic anemia: The hematologist will consider a blood transfusion or a bone marrow transplant to restore the production of healthy blood cells

The animal housed individually in stainless steal cages under controlled condition at constant temperature (22C) and lighting (12 light-dark cycle) and given free access to food and water at all times

Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells

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We have previously demonstrated that enhanced oxidative phosphorylation and reduced dependence on glycolysis is associated with a radioresistant phenotype in oesophageal adenocarcinoma (21, 22) and rectal adenocarcinoma (23), respectively, suggesting that targeting energy metabolism, specifically oxidative phosphorylation, may be an effective strategy to enhance therapeutic response to neoCRT (42)