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These benefits are particularly relevant for individuals with obesity, who often have multiple cardiovascular risk factors

10.1111/apt.16608 20 GaoZ.SongG.-Y.RenL.-P.MaH.-J.MaB.-Q.ChenS.-C

Coverage is available if you meet strict requirements: BMI 30 (or 27 with comorbidity), failed 2+ other weight loss medications, AND tried semaglutide for at least 6 months

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Activation of GLP-1 and GIP receptors has been linked to the regulation of incretin signalling, glucose homeostasis and mechanisms related to the control of appetite and satiety, while activity towards the glucagon receptor has been analysed for its effects on energy expenditure and fat metabolism