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its use is subject to local commissioning decisions and specific clinical criteria
Glucagon-like peptide-1 1 (GLP-1) is an incretin hormone secreted by the intestinal epithelial endocrine L-cells 2 in response to food
The GLP-1 component (glucagon-like peptide-1) slows gastric emptying and reduces appetite
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Tirzepatide is FDA-approved (for diabetes and weight loss, depending on the brand) and works as a dual-agonist, targeting GLP-1 and GIP receptors to reduce appetite, improve insulin response, and support weight loss
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