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In regard to insulinemia, lower insulin response to oral glucose in GIP or GLP-1 receptor KO mice compared to wildtype mice were reported in some but not in all studies

Following 500 mg oral quercetin, maximum plasma concentration of ~15 g/L of aglycone quercetin (~50 nM, T max of 3 h) and 450 g/L of quercetin non-methylated conjugates (T max of 4 h) were found (114)

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If you take other diabetes medications, you may still need to adjust your doses to avoid any risk of hypoglycaemia