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Understanding your genetic profile helps clinicians evaluate whether glutathione supplementation, other antioxidant strategies, or metabolic support medications make sense for your individual physiology
However, for many individuals struggling with severe obesity, lifestyle changes like diet and exercise may not be enough
Moreover, 16 weeks of CLA supplementation (8 g oil/d contain 6.4 g/d net CLA without isomers identified) in obese women with diabetes reduced BMI and total adipose mass, but had no effect on lean body mass [78], which could potentially be due to the effect of CLA on PPAR-, as CLA is modest ligand for PPAR- [79]
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