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Patients treated with dietary supplements containing alpha-lipoic acid, acetyl-L-carnitine, and a vitamin B complex (Tioneural retard), which act synergistically on inflammation of the peripheral nervous system, showed a reduction in the VAS score attributed to neuralgic discomfort

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It is synthesized in L-cells located in the intestinal mucosa, -cells found in the pancreatic islet, and neurons residing in the nucleus of the solitary tract

Tirzepatide has demonstrated consistent and clinically meaningful weight reduction across multiple studies, establishing it as one of the most promising non-surgical pharmacologic options for obesity management (15, 25)

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