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Faras, J

Similar to cagrilintide, pramlintide is primarily eliminated via the kidneys and, in a pharmacokinetic study in participants with type 1 diabetes, no statistically significant differences were noted in total (AUC 0- ) and peak ( C max ) exposure after administration of a single pramlintide 60 g dose in participants with mild, moderate or severe renal impairment compared with those with normal renal function, although inter-patient variability was high [20]

Most evidence comes from lab and animal studies, not controlled human trials

K.Cory-SlechtaD

La ingestin oral crnica de L-carnitina y carbohidratos aumenta el contenido de carnitina muscular y altera el metabolismo del combustible muscular durante el ejercicio en humanos