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The liver stores substantial quantities of vitamin B12, and hepatocellular damagefrom conditions such as cirrhosis, hepatitis, or hepatocellular carcinomacan release these stores into the bloodstream

It ensures the testing results are objective and reliable for research use

Identification of vitamin B12 as a modulator of LRRK2 activity constitutes a huge step forward because it is a neuroprotective vitamin in animal models and has a mechanism unlike that of currently existing inhibitors, Iban Ubarretxena, director of the Biofisika Institute and co-author of the study, said in a press release

Maintaining improvements long-term requires either continued use or transition to lifestyle interventions that sustain AMPK activation (resistance training, caloric cycling)

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