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Early-life stress alters synaptic plasticity and mTOR signaling: correlation with anxiety-like and cognition-related behavior

Average weight loss of 15 to 17 percent of body weight over 68 weeks

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CX3CL1-CX3CR1 is a critical signaling pathway that is disrupted in neurodegenerative conditions and is associated with a strong microglial toxicity (Keren-Shaul et al., 2017)